Yes. I’ve got mine talking to my home assistant, and I’ve actually been able to glance over at it plugged in on my desk to answer a few spontaneous inqueries. Simple things, like “what time is it” or “were the garage lights left on?”: Using PicoCalc with Home Assistant
Though to admit I’m very much in the “satisfaction of making it work” camp still. My ‘fun’ technique/goal has been to find little bits of functionality to add/address without detracting from the current functionality. Hopefully building up to something truly useful someday. Curren’t we’re at: less-useful than a smartwatch, but more useful than a dumb watch 
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My end-goal is to be able to turn my picocalc on, and as soon as it’s connected to a network, become a dashboard/remote control for my Home Assistants devices.