There 100% WILL be people who are doing it. In which case, I know a certain “maker” on this forum who might come up with a very nice modified case with a larger form factor to cater for potential larger HSF setups. 
That said, the flagship unit sounds it sounds like it might possibly be the same specs as the rpi4; just clocked 300MHz higher, in which case it might come overclocked by default.
Before we start a war, this is reminding me of this thread from the gameshell.
I resonate with @Godzil’s words.
It sounds like it’s already going to be plenty powerful.